What is the discrepancy in between quadrivalent recombinant influenza vaccine and standard quadrivalent inactivated influenza vaccine?
Flublok® is produced by recombinant technology, and does not require any egg or influenza virus in the production process. Meanwhile, the traditional influenza vaccine contains inactivated viruses and ovalbumin (an egg protein), and yet the content should be lower throughout repeated purification in the manufacturing procedures. Both vaccines are received by injections, and in general, it will take 2 weeks for the production of antibody to protect against influenza.
Why is it necessary to receive the Flublok®?
Under the pandemic, the mortality rate of the patients who get infected by COVID-19 and influenza will be 6 times higher than those uninfected. It is advised by World Health Organization (WHO) that influenza immunization should be taken every year to avoid infection, and could also lower the risk of heart attack. Flublok® is approved by USA FDA in 2017, and is a non-egg-based vaccine, thus any person suffering from egg allergy can receive the vaccine.
What is the composition of quadrivalent recombinant influenza vaccine?
The quadrivalent recombinant influenza vaccine advised by the Centre for Health Protection for the 2021-22 season contains the following components:
- an A/Wisconsin/588/2019 (H1N1)pdm09-like virus
- an A/Cambodia/e0826360/2020 (H3N2)-like virus
- a B/Washington/02/2019-like virus
- a B/Phuket/3073/2013-like virus